A one-pot route to thioamides discovered by gas-phase studies
Date
Authors
Noor, Asif
Li, Jiawei
Khairallah, George N.
Li, Zhen
Ghari, Hossein
Canty, Allan J.
Ariafard, Alireza
Donnelly, Paul S.
O'Hair, Richard A.J.
Journal Title
Journal ISSN
Volume Title
Publisher
Access Statement
Abstract
A new palladium mediated “one pot” synthesis of thioamides from aromatic carboxylic acids (ArCO2H + RNCS → ArC(S)NHR + CO2) was discovered by gas-phase experiments and theoretical studies. Palladium-mediated decarboxylation of aromatic carboxylic acids followed by addition of substituted isothiocyanates leads to the corresponding thioamide derivatives.
Description
Keywords
Citation
Collections
Source
Chemical Communications
Type
Book Title
Entity type
Publication