Quantification of Thrombus Kinetics Through Inhibiting Receptor Shedding with Label-Free Imaging Flow Assay
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Zheng, Yujie
Montague, Samantha J.
Lim, Yean J.
Gardiner, Elizabeth E.
Lee, Woei Ming
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Chemical and Biological Microsystems Society
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Abstract
In this paper, we use a high resolution multimodality label-free flow imaging assay to investigate the effect of platelet shedding of key adheso-signalling receptors in thrombus formation assay by inhibiting activation-induced metalloproteolytic cleavage of platelet receptors (GPIb of the GPIb-IX-V complex and GPVI).
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Book Title
MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences
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