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Quantification of Thrombus Kinetics Through Inhibiting Receptor Shedding with Label-Free Imaging Flow Assay

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Date

2021

Authors

Zheng, Yujie
Montague, Samantha J.
Lim, Yean J.
Gardiner, Elizabeth E.
Lee, Woei Ming

Journal Title

Journal ISSN

Volume Title

Publisher

Chemical and Biological Microsystems Society

Access Statement

Research Projects

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Abstract

In this paper, we use a high resolution multimodality label-free flow imaging assay to investigate the effect of platelet shedding of key adheso-signalling receptors in thrombus formation assay by inhibiting activation-induced metalloproteolytic cleavage of platelet receptors (GPIb of the GPIb-IX-V complex and GPVI).

Description

Keywords

interferometry, label - free, microfluidics, Platelet, receptor shedding, scattering, thrombus

Citation

URI

http://www.scopus.com/inward/record.url?scp=85136935655&partnerID=8YFLogxK
 https://www.proceedings.com/64786.html
 https://hdl.handle.net/1885/733764579

Collections

ANU Research Publications

Source

Type

Conference paper

Book Title

MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Entity type

Publication

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