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Browsing by Author Gahan, Lawrence

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Altering the substrate specificity of methyl parathion hydrolase with directed evolution

Author(s)Ng, Tee-Kheang; Gahan, Lawrence; Schenk, Gerhard, et al
TypeJournal article
Date Published2015
Date Created-
01_Schenk_Binuclear_Metallohydrolases:_2012.pdf.jpg

Binuclear Metallohydrolases: Complex Mechanistic Strategies for a Simple Chemical Reaction

Author(s)Schenk, Gerhard; Mitic, Natasa; Gahan, Lawrence, et al
TypeJournal article
Date Published2012
Date Created-

Cadmium(II) complexes of the glycerophosphodiester-degrading enzyme GpdQ and a biomimetic N,O ligand

Author(s)Mirams, Ruth E; Smith, Sarah J; Hadler, Kieran S, et al
TypeJournal article
Date Published2008
Date Created-

Comparative investigation of the reaction mechanisms of the organophosphate-degrading phosphotriesterases from Agrobacterium radiobacter (OpdA) and Pseudomonas diminuta (OPH)

Author(s)Pedroso, Marcelo M; Ely, Fernanda; Mitic, Natasa, et al
TypeJournal article
Date Published2014
Date Created-

Determination of the catalytic activity of binuclear metallohydrolases using isothermal titration calorimetry

Author(s)Pedroso, Marcelo M; Ely, Fernanda; Lonhienne, Thierry, et al
TypeJournal article
Date Published2014
Date Created-

Directed evolution combined with rational design increases activity of GpdQ toward a non-physiological substrate and alters the oligomeric structure of the enzyme

Author(s)Yip, Sylvia; Foo, Jee; Schenk, Gerhard, et al
TypeJournal article
Date Published2011
Date Created-

Electronic and geometric structures of the organophosphate-degrading enzyme from Agrobacterium radiobacter (OpdA)

Author(s)Ely, Fernanda; Hadler, Kieran S; Mitic, Natasa, et al
TypeJournal article
Date Published2011
Date Created-

Electronic Structure Analysis of the Dinuclear Metal Center in the Bioremediator Glycerophosphodiesterase (GpdQ) from Enterobacter aerogenes

Author(s)Hadler, Kieran S; Mitic, Natasa; Yip, Sylvia, et al
TypeJournal article
Date Published2010
Date Created-

Enzymatic bioremediation: organophosphate degradation by binuclear metallo-hydrolases

Author(s)Ely, Fernanda; Foo, Jee; Jackson, Colin, et al
TypeJournal article
Date Published2007
Date Created-
02_Daumann_Immobilization_of_the_enzyme_2014.pdf.jpg

Immobilization of the enzyme GpdQ on magnetite nanoparticles for organophosphate pesticide bioremediation

Author(s)Daumann, Lena J; Larrabee, James A; Ollis, David, et al
TypeJournal article
Date Published2014
Date Created-

Mutation of outer-shell residues modulates metal ion co-ordination strength in a metalloenzyme

Author(s)Foo, Jee; Jackson, Colin J; Carr, Paul D, et al
TypeJournal article
Date Published2010
Date Created-

Organophosphate-degrading metallohydrolases: Structure and function of potent catalysts for applications in bioremediation

Author(s)Schenk, Gerhard; Mateen, Irsa; Ng, Tee-Kheang, et al
TypeJournal article
Date Published2016
Date Created-

Phosphate-bound structure of an organophosphate-degrading enzyme from Agrobacterium radiobacter

Author(s)Ely, Fernanda; Pedroso, Marcelo M; Gahan, Lawrence, et al
TypeJournal article
Date Published2012
Date Created-

Promiscuity comes at a price: Catalytic versatility vs efficiency in different metal ion derivatives of the potential bioremediator GpdQ

Author(s)Daumann, Lena J; McCarthy, Bianca Y; Hadler, Kieran S, et al
TypeJournal article
Date Published2013
Date Created-

Spectroscopic and Catalytic Characterization of a Functional Fe III Fe II Biomimetic for the Active Site of Uteroferrin and Protein Cleavage

Author(s)Smith, Sarah J; Peralta, Rosely A; Jovito, Rafael, et al
TypeJournal article
Date Published2012
Date Created-

Spectroscopic and mechanistic studies of dinuclear metallohydrolases and their biomimetic complexes

Author(s)Daumann, Lena J; Schenk, Gerhard; Ollis, David, et al
TypeJournal article
Date Published2014
Date Created-

Structural and Catalytic Characterization of a Heterovalent Mn(II)Mn(III) Complex That Mimics Purple Acid Phosphatases.

Author(s)Smith, Sarah J; Riley, Mark J; Noble, Christopher J., et al
TypeJournal article
Date Published2009
Date Created-

Structural Flexibility Enhances the Reactivity of the Bioremediator Glycerophosphodiesterase by Fine-Tuning its Mechanism of Hydrolysis

Author(s)Hadler, Kieran S; Mitic, Natasa; Ely, Fernanda, et al
TypeJournal article
Date Published2009
Date Created-
01_Hadler_Substrate-promoted_formation_2008.pdf.jpg

Substrate-promoted formation of a catalytically competent binuclear center and regulation of reactivity in a glycerophosphodiesterase from Enterobacter aerogenes

Author(s)Hadler, Kieran S; Tanifum, Eric A; Yip, Sylvia, et al
TypeJournal article
Date Published2008
Date Created-

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