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Showing results 8 to 27 of 47

The Effects of Severe Hypoxia on Glycolytic Flux and Enzyme Activity in a Model of Solid Tumors

Author(s)Smith, Hannah; Board, Mary; Pellagatti, Andrea, et al
TypeJournal article
Date PublishedAug-2016
Date Created-

Exploiting the metabolic energy demands of drug efflux pumps provides a strategy to overcome multidrug resistance in cancer

Author(s)Gao, Xuexin; Aguanno, Doriane; Board, Mary, et al
TypeJournal article
Date Published2021
Date Created-

Exploring the possible interaction between anti-epilepsy drugs and multidrug efflux pumps; in vitro observations

Author(s)Rivers, Francesca; O'Brien, Terence J.; Callaghan, Richard
TypeJournal article
Date Published2008
Date Created-
01_Yuan_Fabrication_of_psoralen-loaded_2018.pdf.jpg

Fabrication of psoralen-loaded lipid-polymer hybrid nanoparticles and their reversal effect on drug resistance of cancer cells

Author(s)Yuan, Yueling; Chiba, Peter; Cai, Tiange, et al
TypeJournal article
Date Published2018
Date Created-

Generating Inhibitors of P-Glycoprotein: Where to, Now?

Author(s)Crowley, Emily; McDevitt, Christopher A.; Callaghan, Richard
TypeJournal article
Date Published2010
Date Created-

Improving the stability and function of purified ABCB1 and ABCA4: The influence of membrane lipids

Author(s)Pollock, Naomi L.; McDevitt, Christopher A.; Collins, Ricahrd, et al
TypeJournal article
Date Published2014
Date Created-

Inhibition of the multidrug resistance P-glycoprotein: time for a change of strategy?

Author(s)Luk, F; Bebawy, Mary; Callaghan, Richard
TypeJournal article
Date Published2014
Date Created-

Is ATP binding responsible for initiating drug translocation by the multidrug transporter ABCG2?

Author(s)McDevitt, Christopher A.; Crowley, Emily; Hobbs, Gemma, et al
TypeJournal article
Date Published2008
Date Created-

Just How and Where Does P-glycoprotein Bind All Those Drugs?

Author(s)Mittra, Rituparna; Coyle, Elizabeth; Callaghan, Richard
TypeBook chapter
Date Published2016
Date Created-

Location of contact residues in pharmacologically distinct drug binding sites on P-glycoprotein

Author(s)Mittra, Rituparna; Pavy, Megan; Subramanian, Nandhitha, et al
TypeJournal article
Date Published2017
Date Created-

Mamma Mia, P-glycoprotein binds again

Author(s)Callaghan, Richard; Gelissen, Ingrid; George, Anthony M., et al
TypeJournal article
Date Published2020
Date Created-

Metabolic Alterations During the Growth of Tumour Spheroids

Author(s)Bloch, Katarzyna; Smith, Hannah; van Hamel Parsons, Victoria, et al
TypeJournal article
Date Published2014
Date Created-
1-s2.0-S1046202317304462-main.pdf.jpg

Methods of reconstitution to investigate membrane protein function

Author(s)Skrzypek, Ruth; Iqbal, Shagufta; Callaghan, Richard
TypeJournal article
Date Published16-Feb-2018
Date Created-
01_Crowley_Multidrug_efflux_pumps:_drug_2010.pdf.jpg

Multidrug efflux pumps: drug binding - gates or cavity?

Author(s)Crowley, Emily; Callaghan, Richard
TypeJournal article
Date Published2010
Date Created-
01_Chai_New_evidence_for_p-gp-mediated_2021.pdf.jpg

New evidence for p-gp-mediated export of amyloid-β peptides in molecular, blood-brain barrier and neuronal models

Author(s)Chai, Amanda B.; Hartz, Anika M. S.; Gao, Xuexin, et al
TypeJournal article
Date Published2021
Date Created-

A Novel Class of N-Sulfonyl and N-Sulfamoyl Noscapine Derivatives that Promote Mitotic Arrest in Cancer Cells

Author(s)Yong, Cassandra; Devine, Shane M.; Gao, Xuexin, et al
TypeJournal article
Date Published2019
Date Created-

Overcoming ABCG2-mediated drug resistance with imidazo-[1,2-b]-pyridazine-based Pim1 kinase inhibitors

Author(s)Darby, Richard A. J.; Unsworth, Amanda; Knapp, Stefan, et al
TypeJournal article
Date Published2015
Date Created-

Overcoming P-Glycoprotein-Mediated Drug Resistance with Noscapine Derivatives

Author(s)Muthiah, Divya; Henshaw, Georgia; DeBono, Aaron J., et al
TypeJournal article
Date Published2019
Date Created-

P-glycoprotein Inhibition: The Past, the Present and the Future

Author(s)Darby, Richard A. J.; McMahon, Roisin M.; Callaghan, Richard
TypeJournal article
Date Published2011
Date Created-

P-glycoprotein: a role in the export of amyloid-beta in Alzheimer's disease?

Author(s)Chai, Amanda B.; Leung, Gavin K. F.; Callaghan, Richard, et al
TypeJournal article
Date Published2020
Date Created-

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