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Abstract PR13:Inhibition of RNA polymerase I transcription activates targeted DNA damage response and enhances the efficacy of PARP inhibitors in high-grade ovarian cancer

Author(s)Sanij, Elaine; Hannan, Katherine; Xuan, Jiachen, et al
TypeJournal article
Date Published2020
Date Created-

AKT induces senescence in human cells via mTORC1 and p53 in the absence of DNA damage: Implications for targeting mTOR during malignancy

Author(s)Astle, Megan V.; Hannan, Katherine; Ng, PY, et al
TypeJournal article
Date Published2012
Date Created-

AKT signalling is required for ribosomal RNA synthesis and progression of Eμ-Myc B-cell lymphoma in vivo

Author(s)Devlin, Jennifer; Hannan, Katherine; Ng, Pui Y., et al
TypeJournal article
Date Published2013
Date Created-

Cell cycle and growth stimuli regulate different steps of RNA polymerase I transcription

Author(s)Hung, Sandy S.-C.; Lesmana, Analie; Peck, Abigail, et al
TypeJournal article
Date Published2017
Date Created-
01_Devlin_Combination_Therapy_2015.pdf.jpg

Combination Therapy Targeting Ribosome Biogenesis and mRNA Translation Synergistically Extends Survival in MYC-Driven Lymphoma

Author(s)Devlin, J. R.; Hannan, Katherine; Hein, Nadine, et al
TypeJournal article
Date Published21-Oct-2015
Date Created-

Dysregulation of RNA polymerase I transcription during disease

Author(s)Hannan, Katherine; Sanij, Elaine; Rothblum, Lawrence I., et al
TypeJournal article
Date Published2013
Date Created-

High-Content Imaging Approaches to Quantitate Stress-Induced Changes in Nucleolar Morphology

Author(s)He, Jinshu; Soo, Priscilla; Evers, Maurits, et al
TypeJournal article
Date Published2018
Date Created-
TMP4886691142023717141313.pdf.jpg

A High-Throughput Screening Approach to Identify Therapeutics for the Treatment of Diamond-Blackfan Anaemia

Author(s)Núñez Villacís, Lorena; J Al-Obaidi, Sheren; Madhamshettiwar, Piyush, et al
TypeJournal article
Date Published2018
Date Created-
01_Hein_Inhibition_of_Pol_I_2017.pdf.jpg

Inhibition of Pol I Transcription a New Chance in the Fight Against Cancer

Author(s)Hein, Nadine; Hannan, Katherine; D'Rozario, James, et al
TypeJournal article
Date Published2017
Date Created-

Inhibition of Pol I transcription treats murine and human AML by targeting the leukemia-initiating cell population

Author(s)Hein, Nadine; Cameron, Donald; Hannan, Katherine, et al
TypeJournal article
Date Published2017
Date Created-
s41467-019-12971-3.pdf.jpg

The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35

Author(s)Liu, Pei Y.; Tee, Andrew E.; Milazzo, Giorgio, et al
TypeJournal article
Date Published2019
Date Created-
1-s2.0-S0888754322001756-main.pdf.jpg

A new method for determining ribosomal DNA copy number shows differences between Saccharomyces cerevisiae populations

Author(s)Sharma, Diksha; Denmat, Sylvie Hermann-Le; Matzke, Nicholas J., et al
TypeJournal article
Date Published2022
Date Created-

New Roles for the Nucleolus in Health and Disease

Author(s)Núñez Villacís, Lorena; Wong, Mei Szin; Ferguson, Laura, et al
TypeJournal article
Date Published2018
Date Created-
01_Somers_A_novel_small_molecule_that_2019.pdf.jpg

A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction

Author(s)Somers, Klaartje; Wen, V. W.; Middlemiss, S. M. C., et al
TypeJournal article
Date Published22-Jan-2019
Date Created-
01_Yan_The_potential_of_targeting_2017.pdf.jpg

The potential of targeting ribosome biogenesis in high-grade serous ovarian cancer

Author(s)Yan, Shunfei; Frank, Daniel; Son, Jinbae, et al
TypeJournal article
Date Published2017
Date Created-
genes-12-00763.pdf.jpg

The ribosomal gene loci—the power behind the throne

Author(s)Panov, Konstantin; Hannan, Katherine; Hannan, Ross, et al
TypeJournal article
Date Published2021
Date Created-

RNA polymerase I transcription in confluent cells: Rb downregulates rDNA transcription during confluence-induced cell cycle arrest

Author(s)Hannan, Katherine; Kennedy, Brian K.; Cavanaugh, Alice H., et al
TypeJournal article
Date Published2000
Date Created-

S6 Kinase is essential for MYC-dependent rDNA transcription in Drosophila

Author(s)Mitchell, Naomi; Tchoubrieva, Elissaveta B; Chahal, Arjun, et al
TypeJournal article
Date Published2015
Date Created-

Small-Molecule Inhibition of PRMT5 Induces Translational Stress and p53 in JAK2V617F Mutant Myeloproliferative Neoplasms

Author(s)Sonderegger, Stefan; Cerruti, Loretta; Tremblay, Cedric, et al
TypeJournal article
Date Published2018
Date Created-

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