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Showing results 1 to 20 of 46
01_Mellor_Accumulation_and_distribution_2011.pdf.jpg

Accumulation and distribution of doxorubicin in tumour spheroids: the influence of acidity and expression of P-glycoprotein

Author(s)Mellor, Howard R.; Callaghan, Richard
TypeJournal article
Date Published2011
Date Created-

Acetoacetate is a more efficient energy-yielding substrate for human mesenchymal stem cells than glucose and generates fewer reactive oxygen species

Author(s)Board, Mary; Lopez, Colleen; van den Bos, Christian, et al
TypeJournal article
Date Published2017
Date Created-
01_Rottet_Characterisation_of_Hybrid_2020.pdf.jpg

Characterisation of Hybrid Polymersome Vesicles Containing the Efflux Pumps NaAtm1 or P-Glycoprotein

Author(s)Rottet, Sarah; Iqbal, Shagufta; Beales, Paul, et al
TypeJournal article
Date Published2020
Date Created-
01_Callaghan_Collateral_sensitivity_as_a_2012.pdf.jpg

Collateral sensitivity as a strategy against cancer multidrug resistance

Author(s)Pluchino, Kristen M.; Hall, Matthew D.; Goldsborough, Andrew S., et al
TypeJournal article
Date Published2012
Date Created-

Cross-linking, DEER-spectroscopy and molecular dynamics confirm the inward facing state of P-glycoprotein in a lipid membrane

Author(s)Carey Hulyer, Alex; Briggs, Deborah A; O'Mara, Megan, et al
TypeJournal article
Date Published2020
Date Created-

Cytosolic region of TM6 in P-glycoprotein: Topographical analysis and functional perturbation by site directed labeling

Author(s)Storm, Janet; Modok, Szabolcs; O'Mara, Megan, et al
TypeJournal article
Date Published2008
Date Created-
1-s2.0-S0014299917305769-main.pdf.jpg

Dual effects of the PI3K inhibitor ZSTK474 on multidrug efflux pumps in resistant cancer cells

Author(s)Muthiah, Divya; Callaghan, Richard
TypeJournal article
Date Published15-Nov-2017
Date Created-

The Effects of Severe Hypoxia on Glycolytic Flux and Enzyme Activity in a Model of Solid Tumors

Author(s)Smith, Hannah; Board, Mary; Pellagatti, Andrea, et al
TypeJournal article
Date PublishedAug-2016
Date Created-

Exploiting the metabolic energy demands of drug efflux pumps provides a strategy to overcome multidrug resistance in cancer

Author(s)Gao, Xuexin; Aguanno, Doriane; Board, Mary, et al
TypeJournal article
Date Published2021
Date Created-

Exploring the possible interaction between anti-epilepsy drugs and multidrug efflux pumps; in vitro observations

Author(s)Rivers, Francesca; O'Brien, Terence J.; Callaghan, Richard
TypeJournal article
Date Published2008
Date Created-
01_Yuan_Fabrication_of_psoralen-loaded_2018.pdf.jpg

Fabrication of psoralen-loaded lipid-polymer hybrid nanoparticles and their reversal effect on drug resistance of cancer cells

Author(s)Yuan, Yueling; Chiba, Peter; Cai, Tiange, et al
TypeJournal article
Date Published2018
Date Created-

Generating Inhibitors of P-Glycoprotein: Where to, Now?

Author(s)Crowley, Emily; McDevitt, Christopher A.; Callaghan, Richard
TypeJournal article
Date Published2010
Date Created-

Improving the stability and function of purified ABCB1 and ABCA4: The influence of membrane lipids

Author(s)Pollock, Naomi L.; McDevitt, Christopher A.; Collins, Ricahrd, et al
TypeJournal article
Date Published2014
Date Created-

Inhibition of the multidrug resistance P-glycoprotein: time for a change of strategy?

Author(s)Luk, F; Bebawy, Mary; Callaghan, Richard
TypeJournal article
Date Published2014
Date Created-

Is ATP binding responsible for initiating drug translocation by the multidrug transporter ABCG2?

Author(s)McDevitt, Christopher A.; Crowley, Emily; Hobbs, Gemma, et al
TypeJournal article
Date Published2008
Date Created-

Just How and Where Does P-glycoprotein Bind All Those Drugs?

Author(s)Mittra, Rituparna; Coyle, Elizabeth; Callaghan, Richard
TypeBook chapter
Date Published2016
Date Created-

Location of contact residues in pharmacologically distinct drug binding sites on P-glycoprotein

Author(s)Mittra, Rituparna; Pavy, Megan; Subramanian, Nandhitha, et al
TypeJournal article
Date Published2017
Date Created-

Mamma Mia, P-glycoprotein binds again

Author(s)Callaghan, Richard; Gelissen, Ingrid; George, Anthony M., et al
TypeJournal article
Date Published2020
Date Created-

Metabolic Alterations During the Growth of Tumour Spheroids

Author(s)Bloch, Katarzyna; Smith, Hannah; van Hamel Parsons, Victoria, et al
TypeJournal article
Date Published2014
Date Created-
1-s2.0-S1046202317304462-main.pdf.jpg

Methods of reconstitution to investigate membrane protein function

Author(s)Skrzypek, Ruth; Iqbal, Shagufta; Callaghan, Richard
TypeJournal article
Date Published16-Feb-2018
Date Created-

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