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Showing results 1 to 20 of 33

Accumulation and distribution of doxorubicin in tumour spheroids: the influence of acidity and expression of P-glycoprotein

Author(s)Mellor, Howard R.; Callaghan, Richard
TypeJournal article
Date Published2011
Date Created-

Collateral sensitivity as a strategy against cancer multidrug resistance

Author(s)Pluchino, Kristen M.; Hall, Matthew D.; Goldsborough, Andrew S., et al
TypeJournal article
Date Published2012
Date Created-

Cytosolic region of TM6 in P-glycoprotein: Topographical analysis and functional perturbation by site directed labeling

Author(s)Storm, Janet; Modok, Szabolcs; O'Mara, Megan, et al
TypeJournal article
Date Published2008
Date Created-
1-s2.0-S0014299917305769-main.pdf.jpg

Dual effects of the PI3K inhibitor ZSTK474 on multidrug efflux pumps in resistant cancer cells

Author(s)Muthiah, Divya; Callaghan, Richard
TypeJournal article
Date Published15-Nov-2017
Date Created-

The Effects of Severe Hypoxia on Glycolytic Flux and Enzyme Activity in a Model of Solid Tumors

Author(s)Smith, Hannah; Board, Mary; Pellagatti, Andrea, et al
TypeJournal article
Date PublishedAug-2016
Date Created-

Exploring the possible interaction between anti-epilepsy drugs and multidrug efflux pumps; in vitro observations

Author(s)Rivers, Francesca; O'Brien, Terence J.; Callaghan, Richard
TypeJournal article
Date Published2008
Date Created-
01_Yuan_Fabrication_of_psoralen-loaded_2018.pdf.jpg

Fabrication of psoralen-loaded lipid-polymer hybrid nanoparticles and their reversal effect on drug resistance of cancer cells

Author(s)Yuan, Yueling; Chiba, Peter; Cai, Tiange, et al
TypeJournal article
Date Published2018
Date Created-

Generating Inhibitors of P-Glycoprotein: Where to, Now?

Author(s)Crowley, Emily; McDevitt, Christopher A.; Callaghan, Richard
TypeJournal article
Date Published2010
Date Created-

Improving the stability and function of purified ABCB1 and ABCA4: The influence of membrane lipids

Author(s)Pollock, Naomi L.; McDevitt, Christopher A.; Collins, Ricahrd, et al
TypeJournal article
Date Published2014
Date Created-

Inhibition of the multidrug resistance P-glycoprotein: time for a change of strategy?

Author(s)Luk, F; Bebawy, Mary; Callaghan, Richard
TypeJournal article
Date Published2014
Date Created-

Is ATP binding responsible for initiating drug translocation by the multidrug transporter ABCG2?

Author(s)McDevitt, Christopher A.; Crowley, Emily; Hobbs, Gemma, et al
TypeJournal article
Date Published2008
Date Created-

Metabolic Alterations During the Growth of Tumour Spheroids

Author(s)Bloch, Katarzyna; Smith, Hannah; van Hamel Parsons, Victoria, et al
TypeJournal article
Date Published2014
Date Created-
1-s2.0-S1046202317304462-main.pdf.jpg

Methods of reconstitution to investigate membrane protein function

Author(s)Skrzypek, Ruth; Iqbal, Shagufta; Callaghan, Richard
TypeJournal article
Date Published16-Feb-2018
Date Created-
METHODS_2017_236_Submitted.pdf.jpg

Methods of reconstitution to investigate membrane protein function

Author(s)Skrzypek, Ruth; Iqbal, Shagufta; Callaghan, Richard
TypeJournal article
Date Published16-Feb-2018
Date Created-

Multidrug efflux pumps: drug binding - gates or cavity?

Author(s)Crowley, Emily; Callaghan, Richard
TypeJournal article
Date Published2010
Date Created-

Overcoming ABCG2-mediated drug resistance with imidazo-[1,2-b]-pyridazine-based Pim1 kinase inhibitors

Author(s)Darby, Richard A. J.; Unsworth, Amanda; Knapp, Stefan, et al
TypeJournal article
Date Published2015
Date Created-

Overcoming P-Glycoprotein-Mediated Drug Resistance with Noscapine Derivatives

Author(s)Muthiah, Divya; Henshaw, Georgia; DeBono, Aaron J., et al
TypeJournal article
Date Published2019
Date Created-

P-glycoprotein Inhibition: The Past, the Present and the Future

Author(s)Darby, Richard A. J.; McMahon, Roisin M.; Callaghan, Richard
TypeJournal article
Date Published2011
Date Created-

P-glycoprotein: So many ways to turn it on

Author(s)Crowley, Emily; Potter, Simon; Kerr, Ian, et al
TypeJournal article
Date Published2008
Date Created-

Providing a molecular mechanism for P-glycoprotein; Why would i bother?

Author(s)Callaghan, Richard
TypeJournal article
Date Published2015
Date Created-

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