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Accepted Manuscript_ACSMedChemLett.pdf.jpg

2-Cyanoisonicotinamide Conjugation: A Facile Approach to Generate Potent Peptide Inhibitors of the Zika Virus Protease

Author(s)Patil, Nitin; Quek, Jun-Ping; Schroeder, Barbara, et al
TypeJournal article
Date Published13-May-2021
Date Created-
d1sc06750h.pdf.jpg

Antiviral cyclic peptides targeting the main protease of SARS-CoV-2

Author(s)Johansen-Leete, Jason; Ullrich, Sven; Fry, Sarah, et al
TypeJournal article
Date Published2022
Date Created-
Angew Chem Int Ed - 2022 - Ullrich - Biocompatible and Selective Generation of Bicyclic Peptides-10.pdf.jpg

Biocompatible and Selective Generation of Bicyclic Peptides

Author(s)Ullrich, Sven; George, Josemon; Coram, Alexandra, et al
TypeJournal article
Date Published24-Oct-2022
Date Created-
handle-1885-196852.pdf.jpg

Biocompatible Macrocyclization between Cysteine and 2-Cyanopyridine Generates Stable Peptide Inhibitors

Author(s)Nitsche, Christoph; Onagi, Hideki; Quek, Jun-Ping, et al
TypeJournal article
Date Published12-Jun-2019
Date Created-
d0sc05125j.pdf.jpg

A biocompatible stapling reaction for in situ generation of constrained peptides

Author(s)Morewood, Richard; Nitsche, Christoph
TypeJournal article
Date Published4-Nov-2020
Date Created-
Manuscript_ACSMedChemLett2020.pdf.jpg

Catching a Moving Target: Comparative Modeling of Flaviviral NS2B-NS3 Reveals Small Molecule Zika Protease Inhibitors

Author(s)Pach, Szymon; Sarter, Tim M; Yousef, Rafe, et al
TypeJournal article
Date Published9-Apr-2020
Date Created-
Angew Chem Int Ed - 2022 - Abdelkader - Genetic Encoding of Cyanopyridylalanine for In‐Cell Protein Macrocyclization by the.pdf.jpg

Genetic Encoding of Cyanopyridylalanine for In-Cell Protein Macrocyclization by the Nitrile-Aminothiol Click Reaction

Author(s)Abdelkader, Elwy; Qianzhu, Haocheng; George, Josemon, et al
TypeJournal article
Date Published31-Jan-2022
Date Created-
10.1016j.bmcl.2020.126965.pdf.jpg

Inhibitors of the Zika virus protease NS2B-NS3

Author(s)Voss, Saan; Nitsche, Christoph
TypeJournal article
Date Published11-Jan-2020
Date Created-

Main protease mutants of SARS-CoV-2 variants remain susceptible to nirmatrelvir

Author(s)Ullrich, Sven; Ekanayake, Kasuni; Otting, Gottfried, et al
TypeJournal article
Date Published15-Apr-2022
Date Created-
Nanoparticular Inhibitors of Flavivirus Proteases_Accepted Manuscript.pdf.jpg

Nanoparticular Inhibitors of Flavivirus Proteases from Zika, West Nile and Dengue Virus Are Cell-Permeable Antivirals

Author(s)Schroeder, Barbara; Demirel, Peter; Fischer, Christina, et al
TypeJournal article
Date Published9-Dec-2021
Date Created-
NMR studies of ligand binding.pdf.jpg

NMR studies of ligand binding

Author(s)Nitsche, Christoph; Otting, Gottfried
TypeJournal article
Date Published2018
Date Created-
De Novo Discovery.pdf.jpg

De Novo Discovery of Nonstandard Macrocyclic Peptides as Noncompetitive Inhibitors of the Zika Virus NS2B-NS3 Protease

Author(s)Nitsche, Christoph; Passioura, Toby; Varava, Paul, et al
TypeJournal article
Date Published2019
Date Created-
Organoarsenic probes to study proteins_Accepted Manuscript.pdf.jpg

Organoarsenic probes to study proteins by NMR spectroscopy

Author(s)Mahawaththa, Mithun; Orton, Henry; Adekoya, Ibidolapo, et al
TypeJournal article
Date Published13-Jan-2022
Date Created-
acs.chemrev.1c00708.pdf.jpg

Paramagnetic Chemical Probes for Studying Biological Macromolecules

Author(s)Miao, Qing; Nitsche, Christoph; Orton, Henry, et al
TypeJournal article
Date Published2022
Date Created-
Accepted Manuscript.pdf.jpg

Peptide-Bismuth Bicycles: In Situ Access to Stable Constrained Peptides with Superior Bioactivity

Author(s)Voss, Saan; Rademann, Jörg; Nitsche, Christoph
TypeJournal article
Date Published26-Nov-2021
Date Created-
Peptide–Bismuth Bicycles Accepted Manuscript.pdf.jpg

Peptide–Bismuth Bicycles: In Situ Access to Stable Constrained Peptides with Superior Bioactivity

Author(s)Voss, Saan; Rademann, Jörg; Nitsche, Christoph
TypeJournal article
Date Published26-Nov-2021
Date Created-
Predicting Antiviral Resistance Mutations Accepted Manuscript.pdf.jpg

Predicting Antiviral Resistance Mutations in SARS-CoV-2 Main Protease with Computational and Experimental Screening

Author(s)Mini Sasi, Vishnu; Ullrich, Sven; Ton, Jennifer, et al
TypeJournal article
Date Published3-Nov-2022
Date Created-
10.1007s12551-019-00508-3.pdf.jpg

Proteases from dengue, West Nile and Zika viruses as drug targets

Author(s)Nitsche, Christoph
TypeJournal article
Date Published26-Feb-2019
Date Created-
Accepted Manuscript_BMCL2020_2.pdf.jpg

The SARS-CoV-2 main protease as drug target

Author(s)Ullrich, Sven; Nitsche, Christoph
TypeJournal article
Date Published1-Sep-2020
Date Created-
ChemBioChem - 2022 - Ullrich - SARS%E2%80%90CoV%E2%80%902 Papain%E2%80%90Like Protease  Structure  Function and Inhibition-4.pdf.jpg

SARS-CoV-2 Papain-Like Protease: Structure, Function and Inhibition

Author(s)Ullrich, Sven; Nitsche, Christoph
TypeJournal article
Date Published2022
Date Created-

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