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The allosteric inhibition of glycine transporter.pdf.jpg

The allosteric inhibition of glycine transporter 2 by bioactive lipid analgesics is controlled by penetration into a deep lipid cavity

Author(s)Wilson, Katie; Mostyn, Shannon N.; Frangos, Zachary J, et al
TypeJournal article
Date Published2021
Date Created-
d0sc02777d.pdf.jpg

Aryl urea substituted fatty acids: A new class of protonophoric mitochondrial uncoupler that utilises a synthetic anion transporter

Author(s)Rawling, Tristan; MacDermott-Opeskin, Hugo; Roseblade, A, et al
TypeJournal article
Date Published2020
Date Created-

Coordination of Substrate Binding and Protonation in the N. gonorrhoeae MtrD Efflux Pump Controls the Functionally Rotating Transport Mechanism

Author(s)Fairweather, Stephen; Gupta, Vrinda; Chitsaz, Mohsen, et al
TypeJournal article
Date Published2021
Date Created-

Cross-linking, DEER-spectroscopy and molecular dynamics confirm the inward facing state of P-glycoprotein in a lipid membrane

Author(s)Carey Hulyer, Alex; Briggs, Deborah A; O'Mara, Megan, et al
TypeJournal article
Date Published2020
Date Created-

The effects of oxidised phospholipids and cholesterol on the biophysical properties of POPC bilayers

Author(s)Schumann-Gillett, Alexandra; O'Mara, Megan
TypeJournal article
Date Published2018
Date Created-

Enzyme inspired polymer functionalized with an artificial catalytic triad

Author(s)Bhaskaran, Ayana; Aitken, Heather; Xiao, Zeyun, et al
TypeJournal article
Date Published2021
Date Created-
High resolution crystal structure.pdf.jpg

High resolution crystal structure of a KRAS promoter G-quadruplex reveals a dimer with extensive poly-A pi-stacking interactions for small-molecule recognition

Author(s)Ou, Arnold; Schmidberger, Jason; Wilson, Katie, et al
TypeJournal article
Date Published2020
Date Created-
01_Mostyn_Identification_of_an_2019.pdf.jpg

Identification of an allosteric binding site on the human glycine transporter, GlyT2, for bioactive lipid analgesics

Author(s)Mostyn, Shannon; Wilson, Katie; Schumann-Gillett, Alexandra, et al
TypeJournal article
Date Published2019
Date Created-
NSL-172126R2_accepted.pdf.jpg

Is protein structure enough? A review of the role of lipids in SLC6 transporter function

Author(s)Schumann-Gillett, Alexandra; Blyth, Mitchell; O'Mara, Megan
TypeJournal article
Date Published2019
Date Created-

Lipid-Based Inhibitors Act Directly on GlyT2

Author(s)Schumann-Gillett, Alexandra; O'Mara, Megan
TypeJournal article
Date Published2019
Date Created-

Location of contact residues in pharmacologically distinct drug binding sites on P-glycoprotein

Author(s)Mittra, Rituparna; Pavy, Megan; Subramanian, Nandhitha, et al
TypeJournal article
Date Published2017
Date Created-

Method for Developing Optical Sensors Using a Synthetic Dye-Fluorescent Protein FRET Pair and Computational Modeling and Assessment

Author(s)Mitchell, Joshua; Zhang, William; Herde, Michel K., et al
TypeBook chapter
Date Published2017
Date Created-

Molecular Determinants for Substrate Interactions with the Glycine Transporter GlyT2

Author(s)Carland, Jane E; Thomas, Michael; Mostyn, Shannon, et al
TypeJournal article
Date Published2017
Date Created-
01_Chitsaz_Multidrug_Resistance_in_2019.pdf.jpg

Multidrug Resistance in Neisseria gonorrhoeae: Identification of Functionally Important Residues in the MtrD Efflux Protein

Author(s)Chitsaz, Mohsen; Booth, Lauren; Blyth, Mitchell, et al
TypeJournal article
Date Published2019
Date Created-
eaaz0404.full.pdf.jpg

A multifunctional surfactant catalyst inspired by hydrolases

Author(s)Nothling, Mitchell D; Xiao, Zeyun; Hill, Nicholas S, et al
TypeJournal article
Date Published2020
Date Created-
01_Chiou_Mutation_p.R356Q_in_the_2019.pdf.jpg

Mutation p.R356Q in the collybistin phosphoinositide binding site is associated with mild intellectual disability

Author(s)Chiou, Tzu-Ting; Long, Philip; Schumann-Gillett, Alexandra, et al
TypeJournal article
Date Published2019
Date Created-

A potential new, stable state of the E-cadherin strand-swapped dimer in solution

Author(s)Schumann-Gillett, Alexandra; Mark, Alan E.; Deplazes, Evelyne, et al
TypeJournal article
Date Published2018
Date Created-
01_Condic-Jurkic_The_reliability_of_molecular_2018.pdf.jpg

The reliability of molecular dynamics simulations of the multidrug transporter P-glycoprotein in a membrane environment

Author(s)Condic-Jurkic, Karmen; Subramanian, Nandhitha; Mark, Alan, et al
TypeJournal article
Date Published25-Jan-2018
Date Created-
5.0040887.pdf.jpg

The role of plasmalogens, Forssman lipids, and sphingolipid hydroxylation in modulating the biophysical properties of the epithelial plasma membrane

Author(s)Wilson, Katie; Fairweather, Stephen; MacDermott-Opeskin, Hugo, et al
TypeJournal article
Date Published2021
Date Created-

Simple Design of an Enzyme-Inspired Supported Catalyst Based on a Catalytic Triad

Author(s)Nothling, Mitchell; Ganesan, Aravindhan; Condic-Jurkic, Karmen, et al
TypeJournal article
Date Published2017
Date Created-

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