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Showing results 1 to 19 of 19

AKT induces senescence in human cells via mTORC1 and p53 in the absence of DNA damage: Implications for targeting mTOR during malignancy

Author(s)Astle, Megan V.; Hannan, Katherine; Ng, PY, et al
TypeJournal article
Date Published2012
Date Created-

AKT signalling is required for ribosomal RNA synthesis and progression of Eμ-Myc B-cell lymphoma in vivo

Author(s)Devlin, Jennifer; Hannan, Katherine; Ng, Pui Y., et al
TypeJournal article
Date Published2013
Date Created-

Cell cycle and growth stimuli regulate different steps of RNA polymerase I transcription

Author(s)Hung, Sandy S.-C.; Lesmana, Analie; Peck, Abigail, et al
TypeJournal article
Date Published2017
Date Created-
01_Devlin_Combination_Therapy_2015.pdf.jpg

Combination Therapy Targeting Ribosome Biogenesis and mRNA Translation Synergistically Extends Survival in MYC-Driven Lymphoma

Author(s)Devlin, J. R.; Hannan, Katherine; Hein, Nadine, et al
TypeJournal article
Date Published21-Oct-2015
Date Created-

Dysregulation of RNA polymerase I transcription during disease

Author(s)Hannan, Katherine; Sanij, Elaine; Rothblum, Lawrence I., et al
TypeJournal article
Date Published2013
Date Created-

High-Content Imaging Approaches to Quantitate Stress-Induced Changes in Nucleolar Morphology

Author(s)He, Jinshu; Soo, Priscilla; Evers, Maurits, et al
TypeJournal article
Date Published2018
Date Created-
01_Hein_Inhibition_of_Pol_I_2017.pdf.jpg

Inhibition of Pol I Transcription a New Chance in the Fight Against Cancer

Author(s)Hein, Nadine; Hannan, Katherine; D'Rozario, James, et al
TypeJournal article
Date Published2017
Date Created-

Inhibition of Pol I transcription treats murine and human AML by targeting the leukemia-initiating cell population

Author(s)Hein, Nadine; Cameron, Donald; Hannan, Katherine, et al
TypeJournal article
Date Published2017
Date Created-

New Roles for the Nucleolus in Health and Disease

Author(s)Núñez Villacís, Lorena; Wong, Mei Szin; Ferguson, Laura, et al
TypeJournal article
Date Published2018
Date Created-
01_Somers_A_novel_small_molecule_that_2019.pdf.jpg

A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction

Author(s)Somers, Klaartje; Wen, V. W.; Middlemiss, S. M. C., et al
TypeJournal article
Date Published22-Jan-2019
Date Created-
01_Yan_The_potential_of_targeting_2017.pdf.jpg

The potential of targeting ribosome biogenesis in high-grade serous ovarian cancer

Author(s)Yan, Shunfei; Frank, Daniel; Son, Jinbae, et al
TypeJournal article
Date Published2017
Date Created-

RNA polymerase I transcription in confluent cells: Rb downregulates rDNA transcription during confluence-induced cell cycle arrest

Author(s)Hannan, Katherine; Kennedy, Brian K.; Cavanaugh, Alice H., et al
TypeJournal article
Date Published2000
Date Created-

S6 Kinase is essential for MYC-dependent rDNA transcription in Drosophila

Author(s)Mitchell, Naomi; Tchoubrieva, Elissaveta B; Chahal, Arjun, et al
TypeJournal article
Date Published2015
Date Created-

Small-Molecule Inhibition of PRMT5 Induces Translational Stress and p53 in JAK2V617F Mutant Myeloproliferative Neoplasms

Author(s)Sonderegger, Stefan; Cerruti, Loretta; Tremblay, Cedric, et al
TypeJournal article
Date Published2018
Date Created-

Suppression of ABCE1-Mediated mRNA Translation Limits N-MYC-Driven Cancer Progression

Author(s)Gao, Jixuan; Jung, MoonSun; Mayoh, Chelsea, et al
TypeJournal article
Date Published2020
Date Created-

Synergistic inhibition of ovarian cancer cell growth by combining selective PI3K/mTOR and RAS/ERK pathway inhibitors

Author(s)Sheppard, Karen E; Cullinane, C; Hannan, Katherine, et al
TypeJournal article
Date Published2013
Date Created-

Targeting the nucleolus for cancer intervention

Author(s)Quin, Jaclyn; Devlin, Jennifer; Cameron, Donald, et al
TypeJournal article
Date Published2014
Date Created-

The mTORC1 inhibitor everolimus prevents and treats E?-Myc lymphoma by restoring oncogene-induced senescence

Author(s)Wall, Meaghan; Poortinga, Gretchen; Stanley, Kym L., et al
TypeJournal article
Date Published2013
Date Created-

The nucleolus: An emerging target for cancer therapy

Author(s)Hein, Nadine; Hannan, Katherine; George, Amee, et al
TypeJournal article
Date Published2013
Date Created-
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